한약성분정보는 ‘운곡본초학 수재 한약재의 화학성분 제 2판(김정훈 외, 도서출판 우석, 2016)’의 내용을 발췌 및 정리하여 게시하였습니다. 해당 한약재에 함유된 성분 중 이차대사산물(secondary metabolites)을 주요 골격으로 구분하여 제시하였습니다 (성분의 골격 분류 방법에는 다양한 의견이 존재함을 일러드립니다).

방풍(防風)류 한약재의 기원 및 유통상황, 한방효능, 형태특징, 감별요점 등은 여기를 참조바랍니다.

written by : Jung-Hoon Kim. Division of Pharmacology, Pusan National Univ.

1. 관방풍(關防風): 방풍(防風) Saposhnikovia divaricata (Turcz.) Schischk.의 뿌리(根)

① Coumarins: ledebouriellol, 4′-O-glucosyl-5-O-methylvisamminol, 3′-O-angeloyl-hamaudol, hamaudol, 3′-O-acetylhamaudol, sec-O-glucosyl-hamaudol, 5-O-methylvisamminol, 4′-O-β-D-glucosyl-5-O-methylvisamminol¹, cimifugin, prim-O-glucosylcimifugin¹, bergapten, psoralen, imperatorin, phellopterin, deltoin, xanthotoxin, anomalin, scopoletin, marmesin, nodakenetin, marmeinen

② Polyacetylenes: panaxynol, falcarinol, falcarindiol, (8E)-heptadeca-1,8-dien-4,6-diyn-3,10-diol

③ Volatile compounds: octanal, β-bisabolene, nonanal, 7-octen-4-ol. hexanal, cuparene, β-eudesmol

④ Steroids: β-sitosterol, β-sitosterol-β-D-glucoside

⑤ Phenolic acids: vanillic acid (4-hydroxy-3-methoxybenzoic acid)

⑥ Fatty acids: lignoceric acid

2. 빈해전호(濱海前胡, 植防風): 갯기름나물(濱海前胡) Peucedanum japonicum Thunb.의 뿌리(根)

① Coumarins: peucedanol, umbelliferone, 3′(S),4′(S)-diisovaleryloxy-3′,4′-dihydroseselin, 3′(S),4′(S)-disenecioyloxy-3′,4′-dihydroseselin, samidin, anomalin, peujaponisin, visnadin

3. 북사삼(北沙參, 海防風): 갯방풍(珊瑚菜) Glehnia littoralis F.Schmidt ex Miq.의 뿌리(根)

3.1. 근(根) 및 근경(根莖)

① Coumarins: psoralen, bergapten, xanthotoxin, isoimperatorin, imperatorin, bergaptin, 9-geranyloxypsoralen, cnidiline, xanthotoxol, alloisoimperatorin, 9-(1,1-dimethylallyl)-4-hydroxypsoralen, marmesin, scopoletin, 7-O-(3,3-dimethylallyl)-scopoletin, ostheol-7-O-β-gentiobioside, hydroxyimperatorin, (S)-peucedanol, (S)-7-O-methylpeucedanol, demethylsuberosin

② Monoterpenes: (+)/(-)-angelicoidenol-2-O-β-D-glucopyranoside, (-)-angelicoidenol-2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, (2R,6S)-bornane-2,6-diol-2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, (2R)-bornane-2,9-diol-2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, (4R)/(4S)-p-menth-1-ene-7,8-diol-8-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside

3.2. 근(根)

① Polyynes: (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol, (10E)-1,10-heptadecadiene-4,6-diyne-3,8,9-triol, (8E)-heptadeca-1,8-dien-4,6-diyn-3,10-diol

② Polyacetylenes: falcarindiol, and (8E)-1,8-heptadecadiene-4,6-diyne-3,10-diol

③ Phenolic acids: salicylic acid, vanillic acid, ferulic acid

④ Volatile compounds: pinene, limonene, spathulenol, oplopenone, panaxynol, hexadecanoic acid, linoleic acid

¹prim-O-glucosylcimifugin(升麻素苷, C₂₂H₂₈O₁₁)과 4′-O-β-D-glucosyl-5-O-methylvisamminol(5-O-甲基维斯阿米醇苷, C₂₂H₂₈O₁₀)의 총량을 0.24% 이상 함유 _{[CP 2015, HKCMMS 2]}