한약성분정보는 ‘운곡본초학 수재 한약재의 화학성분 제 2판(김정훈 외, 도서출판 우석, 2016)’의 내용을 발췌 및 정리하여 게시하였습니다. 해당 한약재에 함유된 성분 중 이차대사산물(secondary metabolites)을 주요 골격으로 구분하여 제시하였습니다 (성분의 골격 분류 방법에는 다양한 의견이 존재함을 일러드립니다).

사삼(沙參)류 한약재의 기원 및 유통상황, 한방효능, 형태특징, 감별요점 등은 여기를 참조바랍니다.

written by : Jung-Hoon Kim. Division of Pharmacology, Pusan National Univ.

1. 북사삼(北沙參): 갯방풍(珊瑚菜) Glehnia littoralis F.Schmidt ex Miq.의뿌리(根)

1.1. 根 및 根莖

① Coumarins: psoralen, bergapten, xanthotoxin, isoimperatorin, imperatorin, bergaptin, 9-geranyloxypsoralen, cnidiline, xanthotoxol, alloisoimperatorin, 9-(1,1-dimethylallyl)-4-hydroxypsoralen, marmesin, scopoletin, 7-O-(3,3-dimethylallyl)-scopoletin, ostheol-7-O-β-gentiobioside, hydroxyimperatorin, (S)-peucedanol, (S)-7-O-methylpeucedanol, demethylsuberosin

② Monoterpenes: (+)/(-)-angelicoidenol-2-O-β-D-glucopyranoside, (-)-angelicoidenol-2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, (2R,6S)-bornane-2,6-diol-2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, (2R)-bornane-2,9-diol-2-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, (4R)/(4S)-p-menth-1-ene-7,8-diol-8-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside

1.2. 根

① Polyynes: (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol, (10E)-1,10-heptadecadiene-4,6-diyne-3,8,9-triol, (8E)-heptadeca-1,8-dien-4,6-diyn-3,10-diol

② Polyacetylenes: falcarinol¹, falcarindiol, (8E)-1,8-heptadecadiene-4,6-diyne-3,10-diol

③ Phenolic acids: salicylic acid, vanillic acid, ferulic acid

1.3. 根 및 地上部

① Volatile compounds: pinene, limonene, spathulenol, oplopenone, panaxynol, hexadecanoic acid, linoleic acid

2. 남사삼(南沙參): 층층잔대(輪葉沙參) Adenophora triphylla (Thunb.) A.DC. 또는 당잔대(沙蔘) Adenophora stricta Miq.의 뿌리(根)

① Steroids: β-sitosterol, β-sitosterol-O-β-D-glucopyranoside

② Triterpenes: taraxerone

③ Fatty acids: octacosanoic acid

¹ falcarinol(法卡林醇, C₁₇H₂₄O)을 0.023% 이상 함유 _{[HKCMMS 3]}