상륙(商陸) Phytolaccae Radix의 화학성분
한약성분정보는 ‘운곡본초학 수재 한약재의 화학성분 제 2판(김정훈 외, 도서출판 우석, 2016)’의 내용을 발췌 및 정리하여 게시하였습니다. 해당 한약재에 함유된 성분 중 이차대사산물(secondary metabolites)을 주요 골격으로 구분하여 제시하였습니다 (성분의 골격 분류 방법에는 다양한 의견이 존재함을 일러드립니다).
상륙(商陸) 한약재의 기원 및 유통상황, 한방효능, 형태특징, 감별요점 등은 여기를 참조바랍니다.
written by : Jung-Hoon Kim. Division of Pharmacology, Pusan National Univ.
1. 자리공(商陸): Phytolacca esculentaVan Houtte [= P. acinosaRoxb.]의 根
1-1. 根 (roots)
① Saponins 및 sapogenins: esculentoside A1, esculentoside B, esculentoside C, esculentoside E (phytolaccoside G), esculentoside F~Q, phytolaccoside E, esculentic acid, phytoloccagenic acid, jaligonic acid (demethyl phytolaccagenin), phytolaccagenin, esculentagenic acid, esculentagenin
② Steroids: 6′-palmityl-α-spinasteryl-β-D-glucoside, α-spinasterol, Δ7-stigmasterol 및 glycosides, acylated steryl glycosides,
③ Fatty acids: palmitic acid, stearic acid, myristic acid
④ Amino acids: γ-aminobutyric acid (GABA)
1-2. 塊根 (tuberous roots)
① Alkanes: 2-ethyl-1-hexanol, 2-methoxy-4-propenylphenol
② Phthalates: dibutylphthalate
③ Fatty acids: ethyl palmitate, ethyloleate, tetradecylpalmitate
④ Quinones: zonarol
⑤ Glycerides: 2-monolinolein
2. 미국자리공(垂序商陸 ; 美洲商陸): P. americana L.의 根
① Saponins 및 sapogenins: phytolaccoside A, phytolaccoside B (phytolaccasaponin G), phytolaccoside D, phytolaccoside E (phytolaccasaponin E), phytolaccoside G (esculentoside E), phytolaccoside D2, phytolaccoside F, phytolaccasaponin B, phytolaccagenin, 2-hydroxyesculentic acid, 3-oxo-30-carbomethoxy-23-norolean-12-en-28-oic acid, esculentic acid, phytolaccagenic acid, oleanolic acid
② Organic acids: pipecolinic acid
③ Amino acids: aspartic acid, glutamic acid, citrulline, γ-glutamylhistidine, γ-aminobutyric acid
④ Steroids: α-spinasterol, Δ7-stigmasterol, α-spinasteryl-β-D-glucoside, Δ 7-stigmastenyl-β-D-glucoside, 6′-palmityl-Δ7-stigmastenyl-β-D-glucoside, 6′-palmityl-α-spinasteryl-β-D-glucoside
⑤ Alkaloidss: phytolaccatoxin
⑥ Flavonoids: xanthomicrol
